Manx Syndrome: a range of conditions seen in the Manx cat and associated lineages, beginning with it's characteristic feature: a shortened tail (or lack thereof). This is a vertebral mutations that affect both the tail and the spinal cord; as such, most common developmental problem seen in Manx cats is spina bifida. Spina bifida is a general term used to describe several conditions where the neural tube which forms the spinal cord fails to close and the arches of the vertebrae (bones of the spine) also fail to form completely. Symptoms include: abnormal "hopping" gait, plantigrade stance (with more of the hind leg on the ground than normal), general incontinence, and lack of sensation in the hind legs. Some cats can be so severely affected that the deformity is fatal.